Risks of non sedating antihistamines
Bilastine is efficacious in all nasal symptoms including obstruction and in eye symptoms.
Because delirium and hallucinations can result from the use of anticholinergics including sedating antihistamines, patients receiving these medications are at risk of being prescribed antipsychotic medications.
Cognitive decline, falls, and behaviors such as hallucinations, delirium, and agitated aggressive behaviors may result in affected patients being hospitalized or admitted to long term care facilities.
Healthcare professionals working in long term care communities and skilled nursing facilities should work with families, prescribers, and other members of the healthcare team to discourage the use of first-generation antihistamines and other highly anticholinergic medications in older patients.
Therefore, it is recommended that bilastine is taken at least one hour before and no sooner than two hours after a meal.
Clinical studies sponsored by the manufacturer have shown that bilastine 20 mg once daily is as efficacious as other nonsedating antihistamines in allergic rhinoconjunctivitis and chronic urticaria in individuals from 12 and 18 years of age, respectively.
H2 blockers (eg, ranitidine, famotidine) commonly are used for the treatment of heartburn and gastroesophageal reflux disease.